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Table of contents
- Donepezil research paper in 2021
- Donepezil 5 mg vs 10 mg
- Donepezil side effects
- Articles on donepezil pdf
- Donepezil mechanism of action
- Donepezil contraindications
- Donepezil uses
- Donepezil classification
Donepezil research paper in 2021
Donepezil 5 mg vs 10 mg
Donepezil side effects
Articles on donepezil pdf
Donepezil mechanism of action
Donepezil contraindications
Donepezil uses
Donepezil classification
How is donepezil used to treat Alzheimer's disease?
Alzheimer’s disease is associated with a reduction in certain cerebral neurotransmitters, including acetylcholine. The aim of donepezil treatment is to inhibit the hydrolysis of acetylcholine, thereby increasing its concentration in the synaptic cleft, and consequently, improving neurotransmission.
Are there any side effects to taking donepezil?
No behavioral benefits were observed, except for -2.72 (95% CI -4.92 to -0.52) in the 10 mg daily donepezil group and -1.72 (95% CI -3.12 to -0.33) for 24 mg daily galantamine trial. Only 5 mg daily donepezil had no effect on the function outcome.
How does donepezil work as a transdermal patch?
The aim of donepezil treatment is to inhibit the hydrolysis of acetylcholine, thereby increasing its concentration in the synaptic cleft, and consequently, improving neurotransmission. It has been hypothesised that donepezil formulated as a transdermal patch, similar to rivastigmine, could provide significant patient benefit.
Last Update: Oct 2021
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